Investigação da influência de estudos etnobiológicos no desenvolvimento de bioinseticidas e perfil toxicológico do extrato aquoso de Lippia sidoides Cham

Abstract

The use of synthetic pesticides is common for maintaining world agricultural production. However, these inputs generate negative effects on the environment and on humans, among which can be mentioned the contamination of aquatic and terrestrial environments, toxicity in dispersing animals, such as bees, and accumulation in the blood of humans and animals, which can cause problems in the System Central Nervous system (CNS), among others. This work aimed to carry out a survey on the main ethnobotanical indications of species of the genus Lippia sp., with emphasis on their use as an insecticide and pesticide, and to relate the influence of these indications with the advances in studies with the pesticidal activity of the genus. In addition, a toxicological profile of the Lippia sidoides Cham species was investigated using different methodologies, with the aim of ensuring the use of this species in traditional medicine and in future studies. The bibliographic survey showed that Lippia species are commonly used by populations to treat various diseases, with the preparation of teas through the leaves being the main form of use L. alba and L. janvica are the most cited species for medicinal use, as well as stand out for use as a repellent and insecticide. Insecticide studies with the genus Lippia sp indicate the species L. sidoides, L. alba and L. janvica as the most investigated. In the toxicological study it was possible to verify that the aqueous extract of L.sidoides does not present a toxicological profile by the different methods used, demonstrating safety for use among traditional communities and promising for the development of scientific studies in the insecticide area.