Avaliação do diagnóstico do mormo

Abstract

Glanders is a highly contagious disease caused by Burkholderia mallei solipeds, a Gram - negative bacterium, not motility and aerobic coccobacillus, primarily infecting horses, donkeys and mules, though humans are considered accidental hosts . The Burkholderia mallei is listed in the list of the World Organisation for Animal Health (OIE) as an important public health disease, and due to its high potential for infection is referred to as a bioterrorism agent. According to the OIE comprises the serological diagnosis, allergy testing and bacterial isolation, and complement fixation, the official test to be performed for trade of animals. This method of diagnosis is recommended in Brazil by Instruction Nº 22, 16 of march of 2018, Ministry of Agriculture, Livestock and Food Supply by its high sensitivity and specificity. According to the OIE comprises the serological diagnosis, allergy testing and bacterial isolation, and complement fixation, the official test to be performed for trade of animals and bacterial isolation is considered gold test for identification of the agent. From the bacterial isolation the presence of Burkholderia was identified in 11 samples from epidemiological surveillance in the disease outbreaks. Sequencing demonstrated the circulation of the strains Burkholderia pseudomallei and Burkholderia mallei in Brazilian territory where Mormo is present. The results show the differentiation of the circulating strains in the national territory and provides the knowledge of their epidemiology and virulence, later assisting in formulations of disease control and eradication measures