Avaliação do protocolo anestésico xilazina, quetamina e remifentanil em cadelas submetidas à ovário- salpingo-histerectomia através da eletrocardiografia

Abstract

Several anesthesic protocols aiming to reduce undisirable haemodinamics effects, allowing safetier return with minimal side effects to patient. Thus, the objective of this study was to evaluate the possible changes in vital parameters related to ECG, heart rate and body temperature in bitches pre-treated with atropine, anesthetized with ketamine and xylazine, associated or not to different doses on a continuous infusion of remifentanil. It was used 15 clinical healthy bitches, distributed acoording to experimental groups: G1= ketamine+ xylazine; G2= ketamine + xylazine + continuous remifentanil infusio(0,125 g/Kg/min); G3 = ketamine + xylazine + continuous remifentanil infusion (0,25 g/Kg/min). The variable measurement was accomplished before pre-anesthesia (M0), simultaneously to skin incision (M1), during the closing of right ovarian pedicle (M2), during the occlusion of the uterine stump (M3) and half for finish of the skin synthesis (M4). Data showed a sudden increasing on average and standard deviation of cardiac frequency in all groups at M1 (178.6 20.6), having decreasing, although with tachycardia tendency until M4 (157.3 18.3). Such M1 elevation is correspondent to surgical cut moment, suggesting the biggest nociceptive moment, following by right pedicle closing M2, (176.0 15.2). It was not observed apnea on animals, just an considerable repiratory decreasing on six animals (6/15) being one of them (1/5) on G1, thre animals (3/5) on G2 and two animals (2/5) on G3. The corporal temperature values measured by rectum did not showed biological significant among groups, keeping these averages compatibles qith physiological parameters for specie. According to the resultspresented one can suggest that the increase in T wave may be related to electrolyte imbalance, and disrritmia heart, being observed framework of hypoxemia. Further studies with a larger number of animals may confirm the efficiency of the anesthetic protocol using atropine, xylazine, ketamine associated with continuous infusion for remifentanil under the effective control of pain.