Perfil metabólico de cabras leiteiras hígidas durante o período de transição

Abstract

The objective of this study was to evaluate the metabolic profile (energetic, proteic, enzymatic, hormonal and mineral) of clinically healthy dairy goats, reared in the semi-arid region of the State of Pernambuco, Brazil, during the transition period. 94 crossbred goats (Saanen, Toggenburg, Pardo Alpina and Alpina Americana), pregnant, multiparous, mostly with twin pregnancy, were submitted to the intensive breeding system. The experimental design consisted of the moments, 30 days before delivery (30dap), 20dap, 10dap, time of delivery (P), 10 days postpartum (10dpp), 20dpp and 30dpp. Energy metabolic metabolites (βHB, AGNES, glucose, fructosamine, cholesterol and triglycerides) were analyzed; Proteins (total protein, albumin, globulin, urea and creatinine); Enzymes (AST, GGT, CK and amylase); Hormones (insulin, cortisol, free T3 and free T4) and minerals (total calcium, ionized calcium, phosphorus, potassium, sodium and chloride). The results were analyzed through analysis of variance at the 5% probability level and by regression analysis. The variables, cholesterol, CK, free T3, free T4, ionized calcium, phosphorus, sodium and potassium did not present physiological adaptive changes during the transition period. At the time of delivery, the highest concentrations (P <0.05) of AGNEs, glucose and cortisol were observed, and the lowest (P <0.05) of total calcium and albumin were observed. In the final stage of gestation, higher concentrations of insulin, creatinine and triglycerides were observed, whereas in the initial phase of lactation the concentrations of βHB, fruitsamine and globulin were higher. The AST, GGT and amylase enzymes showed higher serum lactate activity. The results obtained in this study, in a physiological condition, could be used as an aid tool in the early detection of blood changes, resulting from metabolic imbalances that occurred in the transition period, allowing early therapeutic intervention.