Avaliação da monensina sódica na prevenção da acidose láctica ruminal induzida em caprinos – Parâmetros hematológicos e bioquímicos

Abstract

The objective of this study was to evaluate the use of monensin in the prevention of ruminal acidosis in goats induced by observation of clinical manifestations and biochemical and hematological parameters. We evaluated the clinical features, physical characteristics of the ruminal fluid, ruminal pH measurement, hematological, biochemical and hormonal. 20 goats were used, males, castrated crossbred Anglo-Nubian and Saanen, weighing 30 kg, clinically sadios.Todos animals underwent surgery for implantation of permanent ruminal cannulas. They were divided into two groups of 10 animals, a control group (CG) and a treatment group (GM), he received through the rumen cannula, a dose of 33 mg / animal / day of monensin during the adjustment period of 40 days. The animals were acidosis induced by intra-ruminal administration of sucrose at a dose of 10g/kg body weight at eight o'clock in the morning, before feeding rumen. Later clinical observations were made during the experiment and collection of blood samples occurred at intervals of 4h, 8h, 12h, 24h, 32h, 48h and 72h post-induction (PI). The animals began to show clinical signs such as apathy, appetite capricious and bloat from 4h PI. There was a change in color of ruminal fluid, becoming milky, and a significant decrease in rumen pH (p <0.05) to below six at 4 PI in both groups tested. There was a hemoconcentration in the early stages, a neutrophilic leukocytosis and inversion of the neutrophil: linfóvitos occurred at 4 PI in both groups, returning to normal 72h PI. The values of plasma fibrinogen, serum ALP activity, AST and creatinine remained within normal values. The activity of CK, GGT, the values of urea, glucose and cortisol values were high, but without statistical significance (p> 0.05) between groups. The monensin offered daily for 40 days at a dose of 33mg/animal, did not prevent the onset of ruminal acidosis in goats lactea this study.